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NPA: Dr. Amish Jain
Funding: Heart & Stroke Ontario Clinician Scientist (Phase II) Award
The focus of the IMPRINT research program is to improve the clinical care and reduce the burden of pulmonary heart disease in preterm neonates suffering from pulmonary hypertension. The program’s current studies are:
Prospective observational study to develop robust echocardiographic criteria for early identification of preterm infants at risk of developing chronic pulmonary hypertension PMID: 33789855 | DOI: 10.1136/bmjopen-2020-044924
Funding: Canadian Institutes of Health Research (IHDCYH)–SickKids Foundation Participating sites: 6 NHRC sites across Canada, the United States & Europe
A detailed registry of preterm neonates treated with inhaled nitric oxide Funding: Mallinckrodt Investigator Initiated Research Grant Participating sites: 12 Canadian NHRC sites
NPA: Dr. Dany Weisz
PA: Dr. Amish Jain, Dr. Luc Mertens, Dr. Prakesh Shah
The main objective of this study is to develop an outcome-based definition of ‘significant’ PDA among extremely low gestational age neonates at different postnatal ages. Funding: Canadian Institutes of Health Research Project Grant Participating sites: 17 Canadian NHRC sites
NPA: Dr. Souvik Mitra
PA: Dr. Amish Jain, Dr. Prakesh Shah
The main objective of this registry-based comparative effectiveness research study is to compare the different pharmacotherapeutic practices aimed at closure of patent ductus arteriosus and to evaluate their impact on clinical outcomes in extremely preterm infants (<29 weeks GA) . Funding: Canadian Institutes of Health Research Project Grant Participating sites: 22 Canadian sites
NPA: Dr. Joseph Ting
Participating sites: BC Women’s Hospital and Health Centre & University of Iowa Stead Family Children’s Hospital
NPA: Audrey Hebert
Participating sites: CHU de Québec-Université Laval & University of Iowa Stead Family Children’s Hospital
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Case Report 4: Hemodynamic effects of prostaglandin infusion in refractory severe persistent pulmonary hypertension of the newborn associated with congenital CMV infection
Authors: Sagee Nissimov, Priyanka Kapadia & Amish Jain (Neonatal Intensive Care Unit, Mount Sinai Hospital, Toronto, Ontario, Canada)